Brand name Frisium tablets (DIN 02221799) are being discontinued in Canada. Please see Lundbeck's statement regarding the discontinuation here.
Lundbeck estimates that the remaining supply of Frisium for the Canadian market will be depleted by the end of 2018. This estimate is based current inventory levels and historical usage. The run out date is subject to change if there are unanticipated increases/decreases in demand.
With the advance notice, there is an opportunity to proactively discuss the situation with patients who are stabilized on brand name Frisium and decide when to switch from the branded product to a generic formulation. Patients, their families and healthcare professionals can contact Lundbeck’s Medical Information team
AUGUST 22, 2016
Status as of August 10, 2016:
- The sole manufacturer of vigabatrin is currently out-of-stock
- The major Canadian distributors we have contacted have either very low levels of inventory or have no
- Some pharmacies still have vigabatrin in inventory
- Lundbeck LLC posted a drug shortage notice on drugshortages.ca on August 9. The reason given for
the shortage is “Unexpected manufacturing delays”.
- Both the tablets and the powder formulation (sachets) are listed on the drugshortages.ca reporting
o 500 mg Sabril tablets, drug identification number 02065819, estimated resupply date: Sept. 1
o 500 mg Sabril powder, drug identification number 02068036, estimated resupply date: Sept.
Update: June 23, 2016
via Canadian Epilepsy Alliance Drug Shortage Committee
Clobazam is in short supply, but this drug is still available at some pharmacies. If inventories have become low or depleted at your pharmacy, ask your pharmacist to recheck the status of both generic clobazam and Frisium (brand name) with their suppliers.
Distributors have started receiving shipments this week of generic clobazam (Apo-clobazam, Apotex Inc.). The new stock will be spread across the country. There may restrictions on the amounts available to individual pharmacies until the supply situation stabilizes. A second replenishment of generic clobazam (Apo-clobazam, Apotex Inc.) is expected to arrive at pharmacies by early July.
It is expected that there will also be periodic shipments of the brand name product (Frisium, Lundbeck LLC) over the coming weeks as